| Date | Apr 2 | Total matches | 4 |
| Men's matches | 2 | Women's matches | 2 |
| Singles matches | 3 | Tag Team matches | 0 |
This episode of SmackDown took place on April 2, 2021 and featured 4 matches on the card. All of the matches ended by pinfall, submission, or the rules stipulated by the match. No championships were defended on the card.
The matches featured 14 wrestlers, highlighted by Daniel Bryan, Bianca Belair, Natalya, Dolph Ziggler, Chad Gable, Robert Roode and Otis.
| Men's Singles Street Fight |
4-5-1 (Overall: 9-5-1, Last 5: 2-2-1) |
0-6-1 (Overall: 0-7-1, Last 5: 0-4-1) |
| Women's Singles |
5-0-1 (Overall: 5-4-1, Last 5: 2-2-1) |
0-2 (Overall: 1-2, Last 5: 1-4) |
| Women's Singles |
3-1 (Overall: 5-3, Last 5: 4-1) |
2-8-1 (Overall: 10-8-1, Last 5: 2-2-1) |
| Men's Four on Four Tag Team |