| Date | May 10 | Total matches | 2 |
| Men's matches | 1 | Women's matches | 1 |
| Singles matches | 2 | Tag Team matches | 0 |
This episode of Main Event took place on May 10, 2021 and featured 2 matches on the card. A majority of the matches ended by pinfall, submission, or the rules stipulated by the match, but 1 of the 2 matches ended with a non-finish disqualification or count-out and 1 match had no clear winner. No championships were defended on the card.
The matches featured 4 wrestlers, highlighted by Nikki Cross, Mustafa Ali, Ricochet and Naomi.
| Men's Singles |
2-7-1 (Overall: 2-7-1, Last 5: 1-3-1) Win Probability: 50.0% |
4-6-1 (Overall: 6-7-1, Last 5: 2-2-1) Win Probability: 50.0% |
| Match ended in a Double Count-out |
| Women's Singles |
2-1 (Overall: 2-1, Last 5: 2-3) Win Probability: 43.5% |
2-2 (Overall: 5-7, Last 5: 1-4) Win Probability: 56.5% |