| Date | May 28 | Total matches | 3 |
| Men's matches | 3 | Women's matches | 0 |
| Singles matches | 2 | Tag Team matches | 0 |
This episode of Ring of Honor 506 took place on May 28, 2021 and featured 3 matches on the card. All of the matches ended by pinfall, submission, or the rules stipulated by the match. No championships were defended on the card.
The matches featured 12 wrestlers, highlighted by Brody King, Tony Deppen, Chris Dickinson, Homicide, LSG, O'Shay Edwards, Jay Lethal, Rhett Titus, Tracy Williams and Jonathan Gresham.
Predictability
Somewhat Predictable
(2 of 3 Matches)
Competitions
Usual Singles
Usual Tag
Diversity
Usual Mens
Usual Womens
| Men's Four on Four Tag Team |
(Combined Overall: 6-1-4, Last 5: 6-1-4) Win Probability: 48.4% |
(Combined Overall: 14-20, Last 5: 10-10) Win Probability: 51.6% |
| Men's Singles |
2-2 (Overall: 2-2, Last 5: 2-2) Win Probability: 63.6% |
0-3 (Overall: 0-3, Last 5: 0-3) Win Probability: 36.4% |
| Men's Singles No Disqualification Match |
1-0 (Overall: 1-0, Last 5: 1-0) Win Probability: 50.0% |
0-1 (Overall: 0-1, Last 5: 0-1) Win Probability: 50.0% |